【科研项目】

1. 国家自然科学基金面上项目，82273732，基于适应性随机化理论的混合臂试验设计方法及其因果推断模型研究，2023/01-2026/12，52万元，主持。

2. 国家自然科学基金青年项目，81703322，基于三臂非劣效性临床试验不依从问题的Bayes因果模型及评价方法研究，2018/01-2020/12，20万元，主持。

3. 中国博士后科学基金面上项目，一等资助，2017M610279，基于贝叶斯网络Meta分析的非劣效性评价方法及应用研究，2017/06-2018/09，8万元，主持。

4. 广东省医学科学技术研究基金项目，A2019438，基于 Bayes 因果模型的非劣效临床试验不依从数据评价方法研究，2019/07-2021/06，1万元，主持。

【学术成果】

1. Yu F*, Li  K*, Li S*, Liu J, Zhang Y, Zhou M, Zhao H, Chen H, Wu N, Liu Z#, Su 1. Ying Wu, Liang Zhao, Yan Hou, Kang Li, Xiao-Hua Zhou. Correcting for non-compliance in randomized non-inferiority trials with active and placebo control using structural models. Statistics in Medicine 2015; 34:950-965. （第一作者）
2. Ying Wu, Yiqun Li, Yan Hou, Kang Li, Xiaohua Zhou. Study duration for three-arm non-inferiority survival trials designed for accrual by cohorts. Statistical Methods in Medical Research 2016.03.17（第一作者）
3. Ying Wu, Lu Wang, Zhongyuan Cai, Luqi Bao, Pu Ai, Zisheng Ai. Prevalence and Risk Factors of Low Health Literacy: A Community-Based Study in Shanghai, China. International Journal of Environmental Research and Public Health 2017.06. DOI:10.3390/ijerph14060628. (并列一作)
4. Ying Wu, Zisheng Ai, Guotong Xu. Marital status and survival in patients with non-small cell lung cancer: an analysis of 70006 patients in the SEER database. Oncotarget 2017.10. DOI: 10.18632/oncotarget.21568. （第一作者）
5. Ying Wu, Pu Ai, Zisheng Ai, Guotong Xu. Subthreshold Diode Micropulse Laser versus Conventional Laser Photocoagulation Monotherapy or Combined with Anti-VEGF Therapy for Diabetic Macular Edema: A Bayesian Network Meta-analysis. Biomedicine & Pharmacotherapy 2018;97: 293-299. （第一作者）
6. Li YQ†, Wu Y†, Zhang XH, Bai YF, Akthar LM, Lu X, Shi M, Zhao JX, Jiang QH, Li Y* SCIA: A Novel Gene Set Analysis Applicable to Data With Different Characteristics. Front. Genet. 2019 Jun 25;10:598. (并列一作)
7. Yang K†, Wu Y†, Chen D, Liu S*, Chen R*. The Impact of Lung Function on Extra-Pulmonary Diseases and All-Cause Mortality in US Adult Population with and without COPD. Clin Epidemiol. 2020;12:997-1005
https://doi.org/10.2147/CLEP.S270599. (并列一作)
8. Zhou L†, Wu Y†, Yu S, Shen Y, Ke C. Low-density lipoprotein cholesterol and all-cause mortality: findings from the China health and retirement longitudinal study. BMJ Open. 2020;10(8):e036976. Published 2020 Aug 16. doi:10.1136/bmjopen-2020-036976. (并列一作)
9. Chaofu Ke; Yanan Qiao; Siyuan Liu; Yuqi Rui; Ying Wu *. Longitudinal research on the idirectional association between depression and arthritis, Social Psychiatry and Psychiatric Epidemiology, 2021.Jul, 56(7): 1241-1247.
10. Xiaoyang Jia, Kun Zhang, Minfei Qiang, Ying Wu, Yanxi Chen. Association of Computer-Assisted Virtual Preoperative Planning With Postoperative Mortality and Complications in Older Patients With Intertrochanteric Hip Fracture. JAMA Netw Open. 2020;3(8):e205830. doi:10.1001/jamanetworkopen.2020.5830
11. Jie-Qi Jin, Yue Du, Li-Jun Xu, Zhao-Yue Chen, Jin-Jian Chen, Ying Wu, Chun-Quan Ou. Using Bayesian spatio-temporal model to determine the socio-economic and meteorological factors influencing ambient PM2.5 levels in 109 Chinese cities. Environmental Pollution, 2019; 254, Part A, 113023, ISSN 0269-7491, https://doi.org/10.1016/j.envpol.2019.113023.
12. Ke Chaofu, Li Ang, Hou Yan, Sun Meng, Yang Kai, Cheng Jinlong, Wang Jingtao, Ge Tingting, Zhang Fan, Li Qiang, Li Junnan, Wu Ying, Lou Ge, Li Kang. Metabolic phenotyping for monitoring ovarian cancer patients. Scientific Reports, 2016.3.21.
13. Wei Hai-bo, Lu Xiang-shi, Shang Li-hua, Xu Gang, Hu Jing, Che De-hai, Liu Fang, Wu Ying, Zhang Guang-mei, Yu Yan, Polymorphisms of ERCC1 C118T/C8092A and MDR1 C3435T Predict Outcome of Platinum-based Chemotherapies in Advanced Non-small Cell Lung Cancer: A Meta-analysis. ARCHIVES OF MEDICAL RESEARCH, 2011.7.01;42(5): 412~420.
14. Zhao R, Duan X, Wu Y, Zhang Q, Chen Y. Association of exposure to Chinese famine in early life with the incidence of hypertension in adulthood: A 22-year cohort study. Nutr Metab Cardiovasc Dis. 2019; 29(11): 1237-1244. doi:10.1016/j.numecd.2019.07.008.
15. Liu S, Qiao Y, Zhang Y, Wu Y, Ke C, Shen Y. Combined effect of high depressive symptom burden and hypertension on new-onset stroke: evidence from a nationwide prospective cohort study [published online ahead of print, 2020 Jul 27]. J Hypertens. 2020;10.1097/HJH.0000000000002599. doi:10.1097/HJH.0000000000002599.
16. Zhang, Y., Zhou, L., Liu, S., Qiao, Y., Wu, Y., Ke, C., & Shen, Y. (2020). Prevalence, correlates and outcomes of multimorbidity among the middle-aged and elderly: Findings from the China Health and Retirement Longitudinal Study. Archives of gerontology and geriatrics, 90, 104135. https://doi.org/10.1016/j.archger.2020.104135.
17. 吴莹, 侯艳, 李康. 临床试验中生存分析的非劣效研究设计及R软件实现, 中国卫生统计，2013.06.25，30（3）：438~439
18. 吴莹, 侯艳, 李康. 适应性无缝设计在临床试验中的应用及研究进展, 中国卫生统计，2013.03.25,30(1):140~142
19. 吴莹, 侯艳, 李康. 三臂非劣效临床试验的评价方法, 中国卫生统计, 2013.02.25，30（1）：127~130
20. Handbook of Medical Statistics / edited by Ji-Qian Fang. World Scientific Publishing Co. Pte. Ltd. 26 June 2017.
21. Kai Yang; Ying Wu *. A prognosis-related molecular subtype for early-stage non-small lung cell carcinoma by multi-omics integration analysis, BMC Cancer, 2021, 21(1): 128.
22. Yanpeng Wu; Jianhong Pan; Dong Han; Lixin Li; Yanfei Wu; Rui Liao; Zijie Liu; Dingyun You; Pingyan Chen *; Ying Wu *. Ethnic disparities in stillbirth risk in Yunnan, China: a prospective cohort study, 2010-2018, BMC Public Health, 2021, 21(1): 136.
23. Xiaoyang Jia; Minfei Qiang; Kun Zhang; Qinghui Han; Ying Wu *; Yanxi Chen *. Influence of Timing of Postoperative Weight-Bearing on Implant Failure Rate Among Older Patients With Intertrochanteric Hip Fractures: A Propensity Score Matching Cohort Study. Frontiers in medicine, 2021.Dec, 8: 795595.
24. Juan Chen #; Ying Wu #; Yuelin He; Xiaoqin Feng; Yuqiong Ren; Shiting Liu *. Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children. Frontiers in pediatrics, 2022.Mar, 10: 846411.
25. Lei He #; Yaxuan Pi #; Yi Li #; Ying Wu #; Jingru Jiang; Xiaoming Rong; Jinhua Cai; Zongwei Yue; Jinping Cheng; Honghong Li; Melvin Lee Kiang Chua; Charles B Simone 2nd; Wilbert S Aronow; Simona Lattanzi; Joshua D Palmer; Jan Gaertner; Jon Glass; Pingyan Chen; Yamei Tang*. Efficacy and safety of apatinib in radiation-induced brain injury among head and neck cancer: an open-label, single-arm, phase 2 study. International journal of radiation oncology, biology, physics, 2022.Apr, S0360-3016(22)00268-1.
26. Ying Wu #; Yanpeng Wu; Jie Chen; Pingyan Chen*. A Quantitative Bias Analysis to Assess Constancy Assumption in Non-Inferiority Trials Using Bayesian Hierarchical Models. Statistics in Biopharmaceutical Research, 2022;14(4):473-479.
27. Yuemiao Zhang#, Xupu Ma#, Guanghong Yan#, Ying Wu#, Yanli Chen, Zumi Zhou, Na Wan, Wei Su, Feng-Wei Liu, Mu-Xian Dai, Mei Yang, Chunmei Li, Xuanjing Yu, Liang Zhang, Zhongfang Wang, Tai-Cheng Zhou, Dingyun You, Jia Wei*, Zijie Zhang*, Immunogenicity, durability, and safety of an mRNA and three platform-based COVID-19 vaccines as a third dose following two doses of CoronaVac in China: A randomised, double-blinded, placebo-controlled, phase 2 trial. eClinicalMedicine, 2022;54:101680.
28. Jiangdong Liu, Hang Dong, Mengmeng Li, Ying Wu, Chunlin Zhang, Jinjian Chen, Zhou Yang, Guozhen Lin, De Li Liu, Jun Yang, Projecting the excess mortality due to heatwave and its characteristics under climate change, population and adaptation scenarios, International Journal of Hygiene and Environmental Health, 2023;250:114157.
29. 邢星, 吴莹*, 陈平雁. 配对设计中缺乏差值标准差情况下的样本量估计策略. 中国卫生统计, 2021;38(2): 181-182, 187页.

【研究方向】

1.因果推断方法；

2.医学大数据挖掘分析；

3.临床研究前沿设计方法及统计分析方法

【招生专业】生物医学工程

【联系方式】wuying19890321@gmail.com